Determining the optimal inhibitory frequency for cancerous cells using tumor treating fields (TTFields)

Y Porat, M Giladi, RS Schneiderman, R Blat… - JoVE (Journal of …, 2017 - jove.com
Tumor Treating Fields (TTFields) are an effective treatment modality delivered via the
continuous, noninvasive application of low-intensity (1-3 V/cm), alternating electric fields in
the frequency range of several hundred kHz. The study of TTFields in tissue culture is
carried out using the TTFields in vitro application system, which allows for the application of
electric fields of varying frequencies and intensities to ceramic Petri dishes with a high
dielectric constant (Ɛ> 5,000). Cancerous cell lines plated on coverslips at the bottom of the …